IVIG Provincial Program
Ig Dose Calculator
PBCO is proud to present the New Ig Dose Calculator released June 30, 2021.
The new calculator, which matches the one embedded in the Blood Product Request Portal (BPRP), includes the following upgrades and enhancements:
- - Option to accommodate a broader range of dosages: 0.1 to 5.0 g/kg;
- - An SCIg specific dose calculator with output in grams/week;
- - Ability to select Adult, Child or Pregnant as patient type; and
- - A Dose by Day calculator.
The calculator should not replace sound clinical judgment concerning a patient's unique situation, the aim being to arrive at the lowest possible dose while maintaining clinical efficacy.
If you have any questions or require support please contact the PBCO at This email address is being protected from spambots. You need JavaScript enabled to view it.
Literature Resources
Systematic Reviews | |
Jan 2008 | |
Systematic Review of IVIG for Primary Immunodeficiency Diseases |
Jun 2007 |
Jan 2007 | |
Systematic Review of IVIG for Pemphigus and Pemphigoid Blistering Diseases |
Dec 2006 |
Publications | |
Apr 2002 |
TMS IVIG Request Process • Physician's Order for IVIG Template (Aug 2011)
o To be used as a template for Health Authority Physician IVIG Order Forms. Conditions listed are approved for use of IVIG in BC.
• IVIG Dosing Information for Ordering Physicians Template (Jan 2013)
o Can be used as a communication tool to explain IVIG Dosing based on Adjusted Body Weight Calculation to ordering Physicians.
• IVIG Outcome Questionnaire Template
o To be used for conditions OTHER than Rheumatology and Neuromuscular
• IVIG Hemolysis Letter Template
o Can be used as a communication tool to explain the risk of hemolysis in high dose IVIG therapy in group A, B, and AB patients.
Recommendations, Forms & Templates
Recommendations | Dated |
Jul 2019 |
|
TMS IVIg Request Process | Dated |
Dec 2022 | |
Provincial Screening Request Form |
Dated |
TMS IVIg Screening Request Form For centralized screening of IVIg for all Adult Rheumatology conditions, and Neurology conditions as per the Neurology program guidelines |
Sep 2023 |
Outcome Questionnaires | Dated |
Peripheral Nervous System Conditions: IVIg Outcome Questionnaire To be used for Non-Approved Peripheral Nervous System conditions only. |
Jan 2024 |
Central Nervous System Conditions: IVIg Outcome Questionnaire To be used for Central Nervous System conditions only. |
Sep 2023 |
Rheumatology Conditions: IVIg Outcome Questionnaire To be used for Adult Rheumatology conditions only. |
Sep 2022 |
Order Form Templates |
The following order form templates were developed by PBCO and adopted by Health Authorities as appropriate:
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IVIg Provincial Program
Intravenous Immune Globulin (IVIg) is an expensive and limited resource. It is prepared by several commercial manufacturers who use plasma derived from donors to produce IVIg
The BC Provincial Blood Coordinating Office (PBCO) operates an IVIg Utilization Management Program to ensure that enough IVIg is available for patients likely to benefit from the treatment. The program incorporates the:
- BC Ministry of Health Policy on Health Authority Immune Globulin Utilization Management Directives which requires that requests for IVIG use are screened in hospital Transfusion Medicine Services to make sure that IVIG is used in accordance with the BC IVIg Utilization Management Program Recommendations.
Two specialty panels support centralized screening of select conditions. Additional information regarding the Rheumatology and Neurology Screening Programs are found on the following corresponding pages:
Blood Product Request Portal
The Blood Product Request Portal (BPRP) is a web-based application designed by the BC Provincial Blood Coordinating Office (PBCO) to support health authorities across the province in managing IVIg and SCIg requests, screening and utilization.
Since September 2020, BPRP replaced the IVIG Request Module that was implemented in 2008 to support the BC IVIG Rheumatology as well as the BC IVIG Neuromuscular Neurology provincial programs.
If you have any questions or require support or specific training please contact PBCO at This email address is being protected from spambots. You need JavaScript enabled to view it.