TraQ - BC PBCO

Monthly newsletter - August 2023

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General

High cardiorespiratory fitness may lower risk for certain cancers up to 40% (17 August 2023) | Related:
- Onerup A, Mehlig K, Geijerstam AA, et al. Associations between cardiorespiratory fitness in youth and the incidence of site-specific cancer in men: a cohort study with register linkage. Br J Sports Med. 2023 Aug 15:bjsports-2022-106617. Epub ahead of print. (Free full text) | Pubmed abstract
Why blood type seems to be linked with COVID-19 risk (16 August 2023) | Related:
- Mortensen SJ, Gjerding LAM, Exsteen MB, et al. Reduced susceptibility to COVID-19 associated with ABO blood group and pre-existing anti-A and anti-B antibodies. Immunobiology. 2023 Jul;228(4):152399. Epub 2023 May 30. (Free full text) | Pubmed abstract
Cancers, especially gastro tumors are rising among Americans under 50 (16 August 2023) | Related:
- Koh B, Tan DJH, Ng CH, et al. Patterns in cancer incidence among people younger than 50 years in the US, 2010 to 2019. JAMA Netw Open. 2023 Aug 1;6(8):e2328171. (Free full text) | Pubmed abstract
Pain, fatigue not associated with neurocognitive performance in adolescents with SCD (15 August 2023) | Related:
- Semko JH, Longoria J, Porter J, et al. Examining the influence of pain and fatigue on neurocognitive functioning in adolescents and young adults with sickle cell disease. Pediatr Blood Cancer. 2023 Aug 10:e30621. Epub ahead of print.
WHO reports rising global COVID cases (14 August 2023)
Paroxysmal cold hemoglobinuria: A diagnostic dilemma in a paediatric patient. (14 August 2023)
Momelotinib yields symptom, anemia benefits in pretreated myelofibrosis (14 August 2023) | Related:
- Gerds AT, Verstovsek S, Vannucchi AM, et al. Momelotinib versus danazol in symptomatic patients with anaemia and myelofibrosis previously treated with a JAK inhibitor (MOMENTUM): an updated analysis of an international, double-blind, randomised phase 3 study. Lancet Haematol. 2023 Jul 27:S2352-3026(23)00174-6. Epub ahead of print.
Data updates from the IMerge trial (14 August 2023)
PeriCAR-T practice patterns and survival predictors for all CAR-T patients and postCAR-T failure in aggressive B-NHL (11 August 2023) | Related:
- Zurko J, Nizamuddin I, Epperla N, et al. Peri-CAR-T practice patterns and survival predictors for all CAR-T patients and post-CAR-T failure in aggressive B-NHL. Blood Adv. 2023 Jun 27;7(12):2657-69. (Free full text) | Pubmed abstract
Tirabrutinib generates sustained efficacy in relapsed/refractory PCNSL (11 August 2023) | Related:
- ONO PHARMA USA's tirabrutinib receives orphan drug designation from the FDA for the treatment of primary central nervous system lymphoma. ONO PHARMA USA. News Release. March 23, 2023. Accessed August 10, 2023.
Axi-Cel extends survival vs standard of care for R/R LBCL (11 August 2023) | Related:
- Westin JR, Oluwole OO, Kersten MJ, etal.; ZUMA-7 Investigators; Kite Members. Survival with axicabtagene ciloleucel in large B-cell lymphoma. N Engl J Med. 2023 Jul 13;389(2):148-57. Epub 2023 Jun 5
Burden of aging-related comorbidities higher in women living with HIV (10 August 2023) | Related:
- Collins LF, Palella FJ Jr, Mehta CC, et al. Aging-related comorbidity burden among women and men with or at-rRisk for HIV in the US, 2008-2019. JAMA Netw Open. 2023 Aug 1;6(8):e2327584. (Free full text) | Pubmed abstract
Could the right dietary fat help boost platelet counts? (9 August 2023) | Related:
- Barrachina MN, Pernes G, Becker IC, et al. Efficient megakaryopoiesis and platelet production require phospholipid remodeling and PUFA uptake through CD36. bioRxiv [Preprint]. 2023 Feb 12:2023.02.12.527706.
SCD pain impact associated with social, emotional functioning (9 August 2023) Related:
- Kenney MO, Wilson S, Shah N, et al. Biopsychosocial factors associated with pain and pain-related outcomes in adults and children with Sickle Cell Disease: A Multivariable Analysis of the GRNDaD Multi-Center Registry. J Pain. 2023 Aug 4:S1526-5900(23)00494-7. Epub ahead of print. (Open access) | Pubmed abstract
Tranexamic acid protocol and uterine artery embolization for placenta accreta spectrum: implementation and results (9 August 2023) | Related:
- Munoz JL, Blankenship LM, Ramsey PS, McCann GA. Implementation and outcomes of a uterine artery embolization and tranexamic acid protocol for placenta accreta spectrum. Am J Obstet Gynecol. 2023 Jul;229(1):61.e1-61.e7. Epub 2023 Mar 23.
AABB: In Memoriam: Angelyn Konugres, PhD (9 August 2023)
High prevalence of women with HIV have chronic pain (8 August 2023) | Related:
- Povshedna T, Swann SA, Levy SLA, et al. Global prevalence of chronic pain in women with HIV: A systematic review and meta-analysis. Open Forum Infect Dis. 2023 Jul 15;10(8):ofad350. (Free full text) | Pubmed abstract
Antimicrobial resistance linked to 569,000 deaths in the Americas in 2019 (8 August 2023) | The rankings by attributable mortality rate were generally similar, with Haiti having the highest mortality rate and Canada having the lowest.
Tranexamic acid protocol and uterine artery embolization for placenta accreta spectrum: implementation and results (9 August 2023) | Related:
- Munoz JL, Blankenship LM, Ramsey PS, McCann GA. Implementation and outcomes of a uterine artery embolization and tranexamic acid protocol for placenta accreta spectrum. Am J Obstet Gynecol. 2023 Jul;229(1):61.e1-61.e7. Epub 2023 Mar 23.
Patients with transfusion-dependent thalassemia display mild COVID-19, weakened serological response (8 August 2023) | Related:
- Kumari N, Gomber S, Dewan P, et al. COVID-19 antibody response in patients with thalassemia. Cureus. 2023 Jun 17;15(6):e40567. (Free full text) | Pubmed abstract
Scientists have 'de-aged' older mice through infusion of blood from younger mice! Here’s how (8 August 2023) | Related:
- Zhang B, Lee DE, Trapp A, et al. Multi-omic rejuvenation and life span extension on exposure to youthful circulation. Nat Aging. 2023 Jul 27. Epub ahead of print.
Homoharringtonine-based induction therapy may reduce post-transplant relapse in pediatric AML (8 August 2023) | Related:
- Wang B, Wen X, Zhang R, et al. Homoharringtonine-based induction therapy reduces the recurrence rate of pediatric acute myeloid leukemia after allogeneic hematopoietic stem cell transplantation. Cell Transplant. 2023 Jan-Dec;32:9636897231183559. (Open access) | Pubmed abstract
Conditional approval of Novatis' Adakveo for SCD revoked in Europe by EC (8 August 2023)
Overweight, obesity associated with worse survival outcomes in ALL (7 August 2023) | Related:
- Shimony S, Flamand Y, Valtis YK, et al. Effect of BMI on toxicities and survival among adolescents and young adults treated on DFCI Consortium ALL Trials. Blood Adv. 2023 Jul 11:bloodadvances.2023009976. Epub ahead of print.
Assessing available CAR T-cell agents for DLBCL (7 August 2023)
Leaving an emergency department against medical advice (5 August 2023) | Related:
- Sayed ME, Jabbour E, Maatouk A, et al. Discharge against medical advice from the emergency department: results from a tertiary care hospital in Beirut, Lebanon. Medicine (Baltimore). 2016 Feb;95(6):e2788. (Free full text) | Pubmed abstract
- Dubow D, Propp D, Narasimhan K. Emergency department discharges against medical advice. J Emerg Med. 1992 Jul-Aug;10(4):513-6.
Study finds neurocutaneous syndromes increase childhood cancer risk (5 August 2023) | Related:
- Kampitsi CE, Nordgren A, Mogensen H, et al. Neurocutaneous syndromes, perinatal factors, and the risk of childhood cancer in Sweden. JAMA Netw Open. 2023 Jul 3;6(7):e2325482 (Free full text) | Pubmed abstract
Later, deeper multiple myeloma treatment responses linked to improved outcomes (4 August 2023) | Related:
- Richardson PG, Facon T, Venner CP, et al. Late versus early response and depth of response are associated with improved outcomes in patients with newly diagnosed multiple myeloma enrolled in the TOURMALINE-MM2 trial. eJHaem. Epub 2023 Aug 3. (Open access)
Biochip could detect multiple viruses, cancers, or toxins in minutes (4 August 2023) | Related:
- Hu J, Safir F, Chang K, et al. Rapid genetic screening with high quality factor metasurfaces. Nat Commun. 2023 Jul 26;14(1):4486.(Free full text) | Pubmed abstract
Risk of second primary malignancies after transplant increasing in MM patients (3 August 2023) | Related:
- Takamatsu H, Matsuda T, Mizuno S, et al.; Multiple Myeloma Working Group in the Japanese Society for Transplantation and Cellular Therapy. Changing trends in the risk factors for second primary malignancies after autologous stem cell transplantation for multiple myeloma before and after the introduction of proteasome inhibitors and immunomodulatory drugs. Haematologica. 2023 Jul 20. Epub ahead of print.
Study presents workaround for randomized experiments (3 August 2023) | Related:
- Li KT, Shankar V. A two-step synthetic control approach for estimating causal effects of marketing events. Management Science Epub 2 August 2023
Patients with MM and CLL report blood cancer coach app helpful (3 August 2023) | Related:
- LeBlanc MR, LeBlanc TW, Yang Q, et al. A mobile app to support self-management in patients with multiple myeloma or chronic lymphocytic leukemia: Pilot randomized controlled trial. JMIR Cancer. 2023 Jul 6;9:e44533. (Open access) | Pubmed abstract
Chemo/immunotherapy confers greater therapy-related MDS/AML risk in survivors (3 August 2023) | Related:
- Morton LM, Curtis RE, Linet MS, et al. Trends in risk for therapy-related myelodysplastic syndrome/acute myeloid leukemia after initial chemo/immunotherapy for common and rare lymphoid neoplasms, 2000-2018. EClinicalMedicine. 2023 Jul 5;61:102060. (Open access) | Pubmed abstract
Fully electrical proof-of-concept biosensor for detecting RNA cancer biomarker sequences in solution at the single-molecule level (3 August 2023) | Related:
- Pattiya Arachchillage KGG, Chandra S, Williams A, et al. Electrical detection of RNA cancer biomarkers at the single-molecule level. Sci Rep. 2023 Aug 1;13(1):12428. (Open access) | Pubmed abstract
Adding Venetoclax to FLA-IDA improves overall response rate, but not other measures in AML (3 August 2023) | Related:
- Shahswar R, Beutel G, Gabdoulline R, et al. Fludarabine, cytarabine, and idarubicin with or without venetoclax in patients with relapsed/refractory acute myeloid leukemia. Haematologica. 2023 Jul 20. Epub ahead of print.
Measles was once seen as a childhood disease. Increasingly, adults are susceptible, too (2 August 2023) | Related:
- Mina MJ, Kula T, Leng Y, et al. Measles virus infection diminishes preexisting antibodies that offer protection from other pathogens. Science. 2019 Nov 1;366(6465):599-606. (Free full text) | Pubmed abstract
JNJ-3989 reduces HBsAg, may improve immune control in patients with chronic HBV infection (2 August 2023) | Related:
- Yuen MF, Asselah T, Jacobson IM, et al.; REEF-1 Study Group. Efficacy and safety of the siRNA JNJ-73763989 and the capsid assembly modulator JNJ-56136379 (bersacapavir) with nucleos(t)ide analogues for the treatment of chronic hepatitis B virus infection (REEF-1): a multicentre, double-blind, active-controlled, randomised, phase 2b trial. Lancet Gastroenterol Hepatol. 2023 Jul 10:S2468-1253(23)00148-6. Epub ahead of print.
Disease severity and age, not inhibitors alone, influence quality of life in patients with hemophilia (2 August 2023) | Related:
- Haghpanah S, Naderi M, Kamalian S, et al. The impact of inhibitors on the quality of life in patients with hemophilia. SAGE Open Med. 2023 Jul 10;11:20503121231182284. (Open access) | Pubmed abstract
Gene could lower HIV levels in some people of African descent (2 August 2023) | Related:
- McLaren PJ, Porreca I, Iaconis G, et al. Africa-specific human genetic variation near CHD1L associates with HIV-1 load. Nature. 2023 Aug 2. Epub ahead of print. (Free full text) | Pubmed abstract
UCLA study finds new way to protect livers during transplantation (2 August 2023) | Related:
- Dery KJ, Kojima H, Kageyama S, et al. Alternative splicing of CEACAM1 by hypoxia-inducible factor-1 enhances tolerance to hepatic ischemia in mice and humans. Sci Transl Med. 2023 Aug 2;15(707):eadf2059.
3D-printing system can speed up wound healing (2 August 2023) | Related:
- Li L, Wang Z, Wang K, et al. Paintable bioactive extracellular vesicle ink for wound healing. ACS Appl Mater Interfaces. 2023 May 31;15(21):25427-36. Epub 2023 May 19.
Scientists explore potential of injectable biomaterial for corneal repair (2 August 2023) | Related:
- MacAdam AJ, Marcelo Munoz M, El Hage J, et al. Low energy blue pulsed light-activated injectable materials for restoring thinning corneas Adv Funct Mater Epub 2023 19 July (Open access)
As climate change leads to more and wetter storms, cholera cases are on the rise (1 August 2023)
Caplacizumab effective in treating aTTP along with standard regimen (1 August 2023) | Related:
- Soto-Mora JA, Gómez-Espitia LM, Lasalvia P, et al. Effectiveness and safety of caplacizumab in acquired thrombotic thrombocytopenic purpura: health technology assessment and classification according to the methodology established in Colombia. Int J Technol Assess Health Care. 2023 Jul 21;39(1):e48. (Open access) | Pubmed abstract
Early relapse multiple myeloma cohort shows deepened responses to cilta-cel (1 August 2023):
Hepatitis deaths to eclipse TB, HIV and malaria, WHO says (31 July 2023)
Patients with high-risk disease have lower chances of survival from mantle cell lymphoma (31 July 2023) | Related:
- Scheubeck G, Jiang L, Hermine O, et al. Clinical outcome of Mantle Cell Lymphoma patients with high-risk disease (high-risk MIPI-c or high p53 expression). Leukemia. 2023 Jul 26. Epub ahead of print. (Open access) | Pubmed abstract
Leukemia with IKZF1 deletion benefits from prolonged maintenance therapy (31 July 2023) | Related:
- Pieters R, de Groot-Kruseman H, Fiocco M, et al. Improved outcome for ALL by prolonging therapy for IKZF1 deletion and decreasing therapy for other risk groups. J Clin Oncol. 2023 Jul 17:JCO2202705. Epub ahead of print. (Free full text) | Pubmed abstract
Short bursts of activity daily could reduce cancer risk - study (28 July 2023) | Related:
- Stamatakis E, Ahmadi MN, Friedenreich CM, et al. Vigorous intermittent lifestyle physical activity and cancer incidence among nonexercising adults: The UK Biobank Accelerometry Study. JAMA Oncol. 2023 Jul 27. Epub ahead of print. (Free full text) | Pubmed abstract
Leverage blood donation system to uncover ‘underdiagnosed’ familial hypercholesterolemia (28 July 2023) | Related;
- Jackson CL, Keeton JZ, Eason SJ, et al. Identifying familial hypercholesterolemia using a blood donor screening program with more than 1 million volunteer donors. JAMA Cardiol. 2019 Jul 1;4(7):685-89. (Free full text) | Pubmed abstract
Low-dose aspirin raises bleeding risk in healthy older adults, study finds (27 July 2023) | Related:
- McQuilten ZK, Thao LTP, Pasricha SR, et al. Effect of low-dose aspirin versus placebo on incidence of anemia in the elderly : A secondary analysis of the aspirin in reducing events in the elderly trial. Ann Intern Med. 2023 Jul;176(7):913-21. Epub 2023 Jun 20. Erratum in: Ann Intern Med. 2023 Jul 25;:
No obesity drugs in WHO essential medicines list (27 July 2023)
New protein-based nano-switches could lead to faster, more accurate diagnostic tests (27 July 2023) | Related:
- Guo Z, Smutok O, Ayva CE, et al. Development of epistatic YES and AND protein logic gates and their assembly into signalling cascades. Nat Nanotechnol. 2023 Jul 27. Epub ahead of print.
Harvard researchers develop ink that enables 3D printing of beating heart tissues (27 July 2023) | Related:
- Choi S, Lee KY, Kim SL, et al. Fibre-infused gel scaffolds guide cardiomyocyte alignment in 3D-printed ventricles. Nat Mater. 2023 Jul 27. Epub ahead of print.
Korean team claims to have created the first room-temperature, ambient-pressure superconductor (27 July 2023) | Related:
- Lee SB, Kim JH, Kwon YW. The first room-temperature ambient-pressure superconductor Nat Rev Phys. 22 July 2023. (Free full text)
VTE not associated with all-cause mortality in patients with PNH (27 July 2023)
Hep C has a secret strategy to evade the immune system. And now we know what it is (26 July 2023)
A chance to design better vaccines? (26 July 2023) | Related:
- Flegr J, Králová Lesná I, Zahradník D. Exposing and exploiting host-parasite arms race clues in SARS-CoV-2: a principally new method for improved T cell immunogenicity prediction. Biol Methods Protoc. 2023 Jul 25;8(1):bpad011. (Free full text) | Pubmed abstract
Nanopore tech may control contamination in single-molecule DNA extraction (26 July 2023) | Related:
- Tada A, Takeuchi N, Shoji K, Kawano R. Nanopore filter: A method for counting and extracting single DNA molecules using a biological nanopore. Anal Chem. 2023 Jul 4;95(26):9805-12. Epub 2023 Jun 6.
WHO proposes best practices for clinical trials (24 July 2023)
Microbiome could be key in preventing HIV progression (24 July 2023) | Related:
- Apetrei C, Gaufin T, Brocca-Cofano E, et al. T cell activation is insufficient to drive SIV disease progression. JCI Insight. 2023 Jul 24;8(14):e161111. (Free full text) | Pubmed abstract
Click chemistry helps create sialidase-based anticancer therapy (24 July 2023) | Related:
- Szijj PA, Gray MA, Ribi MK, et al. Chemical generation of checkpoint inhibitory T cell engagers for the treatment of cancer. Nat Chem. 2023 Jul 24. Epub ahead of print. (Open access) | Pubmed abstract
Diabetes study finds a wealth of information at your fingertips (24 July 2023) | Related:
- Shah R, Petch J, Nelson W, et al. Nailfold capillaroscopy and deep learning in diabetes. J Diabetes. 2023 Feb;15(2):145-51. Epub 2023 Jan 15 (Open access) | Pubmed abstract

Canada

Giving what costs us nothing (19 August 2023)
Saanich firefighters giving blood, joining West Kelowna wildfire battle (18 August 2023)
5 ways your blood or plasma donation will help another Canadian in need (8 August 2023)
Meet an Ontario man going 'all in all the time' when it comes to giving blood (4 August 2023)
CNL announces project to significantly increase production of rare medical isotope Actinium-225, a promising new weapon in the fight against cancer (26 July 2023)
Cyber-security demands growing, especially within medical sector (25 July 2023)
First Peoples Wellness Circle gets $1.5M from the federal government to help Indigenous mental health workers (24 July 2023)

ORBCoN resources:

- Stay tuned...

Australia

Ollie’s second life (17 August 2023) | Ollie was diagnosed with immune-mediated thrombocytopenia, where the dog’s immune system destroys the body’s platelets (something in the blood that helps prevent bleeding).
Lifeblood and blood donors are stepping up to fight cancer (11 August 2023)
Opinion: Australia’s blood donors answer our call for Amira (11 August 2023)
Australia’s leading technology fractionator signs US$400m historic joint venture agreement to build 1m litre HaemaFrac® facility in Singapore & Cambodia (7 August 2023)
Everything you need to know about dog blood transfusions (4 August 2023)
Council rolls up sleeves to save lives (2 August 2023)
Australian medical laboratory worker who allegedly swapped tissue samples to damage co-worker’s reputation now ‘banned for life’ from providing health services (2 August 2023)
ADF, US CJTMC ‘Blood Cell’: The lifeblood of medical logistics (1 August 2023) | Affectionately known as the “Blood Cell”, the mix of ADF - Army, U.S. Army and U.S. Navy logisticians hit the “Land Down Under'' running in a race against time to deliver blood and plasma units to blood support detachments and onward to treatment facilities spanning thousands of miles across Australia’s densely populated areas and its inhospitable outback.
Inverloch firey’s commitment to helping others (31 July 2023)

Nigeria

Family solicits N7m for 3 years-old child with hole in heart (14 August 2023) | 7 million Nigerian Naira =$9,152.80 USD

Somalia

Somalia inaugurates national blood bank (9 August 2023)

South Africa

Help save a life (16 August 2023)

Sri Lanka

Leading hospitals run without consultant transfusion physicians (17 August 2023)

Sudan

Doctors: South Darfur running short of med supplies (10 August 2023)

Uganda

Blood shortage hits hospitals (2 August 2023) | Dr. Cyprian Opira, the executive director of St. Mary's Hospital Lacor, said they now encourage caretakers to donate blood.

UK

Pet Blood Bank UK: Stanley House Vets in Barnoldswick holds first blood donation session for dogs (16 August 2023)
Perimenopause periods left me needing a transfusion (16 August 2023)
Crisis in A&E sees blood transfusion deaths up as waits and errors increase (15 August 2023)
UK consortium awarded $1m to develop iPSC platform (9 August 2023)
What Is disease X? U.K. establishes VDEC, new Vaccine Research Center (7 August 2023) | Related:
- UKHSA unveils VDEC in ‘step change’ for UK’s growing vaccine capabilities (7 August 2023)

UK: Infected Blood Inquiry - News**

Hunt says bill for infected blood compensation may be very large (28 July 2023)
Jeremy Hunt says no decision on compensation for infected blood victims (28 July 2023

Ukraine

Four killed in Russian strikes on Ukraine that destroyed blood transfusion centre (6 August 2023)

USA^

Regeneron wins FDA approval for rare immune disease med Veopoz, expects high-dose Eylea decision in the coming weeks (19 August 2023)
The CDC works to overhaul lab operations after COVID test flop (16 August 2023)
A Pennsylvania study suggests links between fracking and asthma, lymphoma in children (16 August 2023)
Metro Detroit family uses drive to boost blood supply (16 August 2023)
Red Cross to open new Wood Village blood donation center on August 21 (16 August 2023)
FDA grants priority review to Servier's ivosidenib tablets in IDH1+ R/R MDS (16 August 2023)
COVID hospitalizations accelerate for fourth straight week (15 August 2023)
CMS officially drops fee for independent dispute resolution back to $50 (15 August 2023)
FDA lifts hold on Arcellx’s Gilead-partnered cancer cell therapy (15 August 2023) | Related:
- Patient death spurs FDA to pause test of Arcellx’s Gilead-partnered cell therapy (20 June 2023)
CDC reports uptick in COVID-19 hospitalizations and deaths (14 August 2023) | Related:
- US COVID markers up slightly again (11 August 2023)
DOJ blasts industry attempt to delay Medicare drug price negotiations (14 August 2023)
FDA puts 2seventy CAR-T trial on hold in wake of patient death (14 August 2023)
Pfizer's elranatamab receives accelerated approval in R/R multiple myeloma (14 August 2023)
Blood drive personal for hometown woman: Blood Connection worker benefited from transfusions when she had COVID (12 August 2023)
HHS warns hospitals about 'smishing' (11 August 2023)
Residents donate blood to American Red Cross (11 August 2023)
Upcoming blood drives in Yuma (11 August 2023)
These 10 medications are likely targets for Medicare price negotiations this fall (10 August 2023)
Veterinary college seeking qualified dogs and cats to become blood donors (10 August 2023)
Biden administration warns states on post-pandemic Medicaid coverage losses (10 August 2023)
Frat bros: blood transfusions needed (10 August 2023)
FDA clears way for Phase 1/2a trial of stem cell therapy for Parkinson’s (9 August 2023) | Related:
- Legumes may lower risk of Parkinson’s symptoms with sleep disorder (8 August 2023)
FDA approves extended Prevymis regimen for HSCT patients at risk for late CMV (9 August 2023)
Blood donations needed at Blood Center of Northcentral Wisconsin (9 August 2023)
Trinity Biotech picks up FDA clearance for haemoglobin analyser (8 August 2023)
FDA clears Abbott Alinity h-series hematology system (7 August 2023)
When cancer strikes twice, Black Americans face higher death rate (7 August 2023) | Related:
- Sung H, Nisotel L, Sedeta E, et al. Racial and ethnic disparities in survival among people with second primary cancer in the US. JAMA Netw Open. 2023 Aug 1;6(8):e2327429. (Free full text) | Pubmed abstract
FDA grants clearance for phase 3 study of Ascentage Pharma Group's lisaftoclax in previously treated CLL/SLL (7 August 2023)
CMS again pauses out-of-network billing arbitration after judge sides with providers (7 August 2023)
3 more cancer drugs in shortage (7 August 2023)
Woman rushed to ER with dangerous hemorrhaging after Kansas Clinic botches abortion (4 August 2023)
FDA issues CRL to BLA resubmission for Mesoblast's remestemcel-L in pediatric steroid-refractory aGVHD (4 August 2023)
CMS releases final rule for medicare hospice payments for FY 2024 (4 August 2023)
How much and why 2024 premiums are expected to grow in Affordable Care Act marketplaces (4 August 2023)
Community raises more than $5k to help Midland area dog that needs surgery, blood transfusion (4 August 2023)
How to help Temecula's blood shortage: RivCo donors sought (4 August 2023)
Woodhaven pub owner supporting New York Blood Centers’ ‘Pint for Pint’ donor campaign (3 August 2023)
Alabama researcher will succeed Fauci in infectious disease post (2 August 2023)
Trios Hospital and the Red Cross partner up for a blood drive after a Trios nurse's son was in a bad accident (2 August 2023)
San Diego Blood Bank joins National Partnership (Blood Emergency Readiness Corps) to send blood where needed (2 August 2023)
FDA guidance on control of DNA reactive (mutagenic) impurities in pharmaceuticals (1 August 2023)
COVID hospital admissions jump in what could be a new norm of summer surges (1 August 2023)
Teleflex wins expanded FDA indication for QuikClot Control+ hemostatic device (1 August 2023)
US News' Best Hospitals 2023-24 Honor Roll (1 August 2023)
Arizona has an urgent need for blood donors. Here's how you can help (1 August 2023)
Tennessee shelter dog saves buddy's life with blood donation (1 August 2023)
Medicaid enrollment and unwinding tracker (31 July 2023)
Town of Brookhaven partners with New York Blood Center to reach It’s 3,000th donation (31 July 2023)
Shasta County cancer survivor shares how blood donations saved his life (31 July 2023)
Preventing pathogens: safeguarding donated blood in the medical minute (28 July 2023)
Mosquitoes that carry West Nile are becoming resistant to insecticides, CDC says (29 July 2023)
Mobile transfusions: Birmingham Fire now using whole blood in ambulances (28 July 2023)
Bipartisan Senate bill aims to bolster drug supply chain by prioritizing U.S. manufacturing (27 July 2023)
Bill to overhaul organ transplant system heads to Biden’s desk (27 July 2023)
NIH grant to find if scale of gene editing changes harmful or helpful (25 July 2023)
U.S. sees biggest rise in COVID-19 hospitalizations since December (25 July 2023)
Growth of telehealth in cancer care continued after initial surge during COVID-19 pandemic (25 July 2023) | Related:
- NCI-funded centers study new ways to apply telehealth across cancer care (25 Jan. 2023)
300+ rural hospitals at immediate risk of closure (25 July 2023)
Early COVID-19 indicators show increase: CDC data (24 July 2023)
Tick bites are sending more people in the Northeast to the emergency room this year (24 July 2023)
FDA head Robert Califf battles misinformation - sometimes with fuzzy facts (24 July 2023)

Industry news\\

Abbott: See USA above
Ascentage Pharma Group: See USA above
Arcellx, Gilead: See USA above
Astellas Pharma/ Poseida Therapeutics: Japan's Astellas Pharma invests $50 M for redefining cancer cell therapy (8 August 2023)
Bavarian Nordic: Bavarian Nordic’s chikungunya vaccine candidate shows promise in late-stage trial (7 August 2023)
China's T-Maximum Biotech selects GenScript CRISPR reagents to target high-grade gliomas (10 August 2023)
CSL aims to get better bang for buck from plasma (15 August 2023)
Gracell drops 3 CAR-T programs in hopes of speeding more advanced assets to the finish line (14 August 2023)
GSK: GSK discovers strain of bacterium that stops malaria transmission (7 August 2023)
HaemaFrac: See Australia above
Janssen: Janssen receives positive CHMP opinion for Talvey in multiple myeloma (25 July 2023) | Janssen has announced that its bi-specific antibody, Talvey (talquetamab), has been recommended by the European Medicines Agency’s (EMA) human medicines committee for use in certain patients with relapsed or refractory multiple myeloma.
Merck: See USA above
Mesoblast: See USA above
Novartis: See General news above
ONO Pharma: See General news above
Pfizer: See USA above
Plasticell, CGT Catapult: See UK above
Regeneron: See USA above
Roche: Roche loses spark for gene therapy, axing hemophilia A candidate from pipeline (27 July 2023)
SeekInCare blood test can detect more than 20 cancer types (7 August 2023) | Related:
- Li S, Ren Q, et al. Integrating multi-omics features for blood-based multi-cancer early detection. ASCO Breakthrough 2023. August 3-5, 2023. Abstract 156.
Servier: See USA above
SPOT-MAS Assay can detect presence, location of multiple cancers (August 9 2023) | Related:
- Early detection of five common cancers using the ctDNA analysing test (K-DETEK)
Teleflix: See USA above
Terumo Blood and Cell Technologies: ' Reveos® automated whole blood processing system cleared by FDA for U.S. commercial use (1 August 2023)
2seventy Bio: See USA above
Therapeutic Solutions: Orphan drug designation sought for stem cell therapy to treat frontotemporal dementia (24 July 2023) | Therapeutic Solutions has filed with the FDA to receive orphan drug designation for its JadiCell adult stem cell therapy for treatment of frontotemporal dementia.
Thermo Fisher’s framework de-risks cell processing equipment selection (9 August 2023)
Trinity Biotech: See USA above
Y2X Life Sciences: 3D-printed COVID-19 breath test takes two breaths and one minute (1 August 2023)

Infectious diseases in the news##

Chikungunya virus: See Industry news above
CMV: See USA above
Cholera: See General news above
Dengue, Zika virus, Chikungunya virus: See Journals below (de Oliveira, et al.)
HBV: See General news above
HIV, HCV: See UK above
Malaria: See Industry news above
Measles: See General news & Journals below
Yellow fever: See Journals below (Gould, et al.)

Resource Library

CANADA:
- CBS: Learning about organ and tissue donation portal (K-12) | Portal created by CBS collaborating with Canada's organ/tissue donation and transplant organizations.
- CBS: Funded research projects
- CBS: FAQ: Information for health professionals on safety of transfused blood collected from COVID-19-vaccinated donors
- Héma-Québec: Multiple videos on [blood donation, plasma donation, stem cell donation, mother's milk donation, sickle cell anemia & more]
- The OrbCon Report June 2023
- BC PBCO:
  - Stay tuned...
Australia/NZ:
- Australian and New Zealand Society of Blood Transfusion:ANZSBT (Multiple guidelines)
- Australian Blood Matters Program (Multiple resources)
- Blood Safe e-Learning Australia
Ireland (HSE): Blood transfusion leaflets (In 7 languages)
ISBT:
- ISBT Code of Ethics (Available in 8 languages)
- Identify critical elements of a scientific manuscript review ( Dr. Ziggy Szczepiorkowski webinar: 47:58 min.)
- ISBT Transfusion Reactions E-learning Module
- ISBT Patient Blood Management Resources
- ISBT Blood transport container validation guidelines (6 pp. pdf)
EBA: European Blood Alliance (Position papers and fact sheets)
UK:
- NEW Annual SHOT Report 2022
- British Society for Haematology guideline for anticoagulant management of pregnant individuals with mechanical heart valves (1 Apr. 2023)
- JPAC
- NHS:
  - Clinical commissioning policy: Treatment of iron overload for transfused and non-transfused patients with chronic inherited anaemias (all ages)
  - Clinical panel report: Treatment of iron overload for transfused and non-transfused patients with chronic inherited anaemias (all ages)
  - Clinical priorities advisory group summary report: Treatment of iron overload for transfused and non-transfused patients with chronic inherited anaemias (all ages)
  - Evidence review: Treatment of iron overload for transfused and non-transfused patients with chronic inherited anaemias (all ages)
  - Engagement report: Treatment of iron overload for transfused and non-transfused patients with chronic inherited anaemias (all ages)
  - Equality and Health Inequalities Impact Assessment (EHIA): Treatment of iron overload for transfused and non-transfused patients with chronic inherited anaemias (all ages)
  - British Society for Haematology (Multiple guidelines)
  - NHSBT: Blood Assist | Covers 8 core stages of blood administration, including positive patient identification, consent, compatibility, transfusion reactions and more.
  - SHOT:
    - SHOT Webinars
  - USA (AABB):
    - AABB: Billing Guide for Blood Products and Related Services (August 2023)
    - AABB publishes new guide to the use of blood warming devices (4 August 2023)
    - AABB's Transfusion publishes The THOR Network 2022 Remote Damage Control Resuscitation Supplement (May 2023) | This open-access supplement features 30 articles on a wide range of disaster preparedness and emergency response topics. Publication is made possible by support provided by the U.S. Army Medical Research and Development Command -- Combat Casualty Care Research Program.
    - Monthly podcasts from the Journal Transfusion
  Journals, etc.++
  
  Free full text papers | * 1 or more Canadian authors
Free sample journal issues:
- Lancet Group publishes the latest monkeypox-related content in all Lancet journals | All monkeypox content is free to access.
- Open access journal: The Lancet Digital Health 2019 May;1(1):e1-e44.
- Open access journal: Hematology, Transfusion and Cell Therapy, Journal of the Brasilian Association of Hematology, Hemotherapy and Cell Therapy (ABHH)
- Transfus Med Hemother 2019 Oct; 46(5): Many open access articles
- Open access journal (May 2020): The Lancet Microbe
Adkins BD, Murfin R, Luu HS, Noland DK. Paediatric clinical decision support: Evaluation of a best practice alert for red blood cell transfusion. Vox Sang. 2023 Jul 11. Epub ahead of print. | Pubmed abstract
Al-Kuran O, Al-Mehaisen L, Qasem R, et al. Distribution of ABO and Rh blood groups among pregnant women attending the obstetrics and gynecology clinic at the Jordan University Hospital. Sci Rep. 2023 Aug 14;13(1):13196. | Pubmed abstract
Arnoni CP, Silva NM, Silva FS, et al. Genetic diversity of Gerbich alleles in Brazilians reveals an unexpected prevalence of the GE:-2,-3,4 phenotype. Vox Sang. 2023 Aug 8. Epub ahead of print. | Pubmed abstract
Benabdallah A, Jellouli T. Application of a cost calculation approach in medical oncology: case of Hassan II university hospital in Morocco. Cost Eff Resour Alloc. 2023 Aug 11;21(1):53. | Pubmed abstract
Bisht A, Arora S, Patidar G, Marwaha N. Knowledge assessment of a donor adverse reaction severity grading tool by the National Blood Donor Vigilance Programme of India. Vox Sang. 2023 Aug 2. Epub ahead of print.
Broderick KC, Burke JP, Fishman J, Gleason PP. Descriptive, real-world treatment patterns, resource use, and total cost of care among eculizumab- and ravulizumab-treated members with paroxysmal nocturnal hemoglobinuria. J Manag Care Spec Pharm. 2023 Aug;29(8):941-51. | Pubmed abstract
Brusilovskaya K, Hofer BS, Simbrunner B, et al. Platelet function decreases with increasing severity of liver cirrhosis and portal hypertension-A prospective study. Thromb Haemost. 2023 Jul 30. Epub ahead of print.
D'Alessandro A. Red blood cell omics and machine learning in transfusion medicine: Singularity is near. Transfus Med Hemother. 2023 Mar 8;50(3):174-83. | Pubmed abstract
Collins LF, Palella FJ Jr, Mehta CC, et al. Aging-related comorbidity burden among women and men with or at-rRisk for HIV in the US, 2008-2019. JAMA Netw Open. 2023 Aug 1;6(8):e2327584. | Pubmed abstract
D'Alessandro A. Red blood cell omics and machine learning in transfusion medicine: Singularity is near. Transfus Med Hemother. 2023 Mar 8;50(3):174-83. | Pubmed abstract
Dery KJ, Kojima H, Kageyama S, et al. Alternative splicing of CEACAM1 by hypoxia-inducible factor-1 enhances tolerance to hepatic ischemia in mice and humans. Sci Transl Med. 2023 Aug 2;15(707):eadf2059.
de Oliveira FN, Ferreira SC, Nishiya AS, et al. Evaluation of Dengue, Zika virus, and Chikungunya virus transmission by blood components in recipients of haematopoietic stem cell transplantation. Transfus Med. 2023 Aug 1. Epub ahead of print.
Dhawan B, Mittal K, Kaur P, et al. Association of blood donor characteristics and in vitro haemolysis of packed red blood cell concentrates during storage. Vox Sang. 2023 Aug 2. Epub ahead of print.
Domanovi D, von Bonsdorff L, Tiberghien P, et al. Plasma collection and supply in Europe: Proceedings of an International Plasma and Fractionation Association and European Blood Alliance symposium. Vox Sang. 2023 Jul 18. Epub ahead of print. | Pubmed abstract
Dubow D, Propp D, Narasimhan K. Emergency department discharges against medical advice. J Emerg Med. 1992 Jul-Aug;10(4):513-6.
Editorial. Burnout in the haematological workforce Lancet Haematol. 2023 Jul;10(7):e477
Edwards AR, Masser BM, Barlow FK. Psychological ownership and identity motives in blood donation. Vox Sang. 2023 Aug;118(8):616-23. Epub 2023 Jun 8. | Pubmed abstract
Farcet MR, Lackner C, Schirmer A, Kreil TR. Tetanus antibodies in normal human immunoglobulin preparations. Vox Sang. 2023 Aug 8. Epub ahead of print.
Fernandez-Sojo J, Valdivia E, Esquirol A, et al. Development of an in-house bone marrow collection kit: The Catalan bone marrow transplantation group experience. Vox Sang. 2023 Aug 2. Epub ahead of print.
Fischer AL, Messer S, Riera R, et al. Antiplatelet agents for the treatment of adults with COVID-19. Cochrane Database Syst Rev. 2023 Jul 25;7(7):CD015078. | Pubmed abstract
Flegr J, Králová Lesná I, Zahradník D. Exposing and exploiting host-parasite arms race clues in SARS-CoV-2: a principally new method for improved T cell immunogenicity prediction. Biol Methods Protoc. 2023 Jul 25;8(1):bpad011. | Pubmed abstract
Focosi D, Meschi S, Coen S, et al. Serum anti-Spike immunoglobulin G levels in random blood donors in Italy: High-titre convalescent plasma is easier than ever to procure. Vox Sang. 2023 Jul 25. Epub ahead of print. | Pubmed abstract
Fontana C, Schiavolin P, Ardemani G, et al. To be born twin: effects on long-term neurodevelopment of very preterm infants-a cohort study. Front Pediatr. 2023 Jul 17;11:1217650. | Pubmed abstract
Frutos MC, Blanco S, Barahona NY, et al. Infection by human polyomaviruses JCPyV and BKPyV in blood donors of Argentina. Vox Sang. 2023 Aug;118(8):695-9. Epub 2023 Jun 20. | Pubmed abstract
Gerds AT, Verstovsek S, Vannucchi AM, et al. Momelotinib versus danazol in symptomatic patients with anaemia and myelofibrosis previously treated with a JAK inhibitor (MOMENTUM): an updated analysis of an international, double-blind, randomised phase 3 study. Lancet Haematol. 2023 Jul 27:S2352-3026(23)00174-6. Epub ahead of print.
Gnanaraj J, Basavarajegowda A, Kayal S, et al. Optimising platelet usage during the induction therapy of acute myeloid leukaemia: Impact of physician education. Transfus Med. 2023 Aug;33(4):290-6. Epub 2023 Mar 21.
Gould CV, Free RJ, Bhatnagar J, et al.; Yellow Fever Vaccine Virus Transplant and Transfusion Investigation Team. Transmission of yellow fever vaccine virus through blood transfusion and organ transplantation in the USA in 2021: report of an investigation. Lancet Microbe. 2023 Aug 3:S2666-5247(23)00170-2. Epub ahead of print. | Pubmed abstract
Guo Z, Smutok O, Ayva CE, et al. Development of epistatic YES and AND protein logic gates and their assembly into signalling cascades. Nat Nanotechnol. 2023 Jul 27. Epub ahead of print.
Haghpanah S, Naderi M, Kamalian S, et al. The impact of inhibitors on the quality of life in patients with hemophilia. SAGE Open Med. 2023 Jul 10;11:20503121231182284. | Pubmed abstract
Hang NTL, Hijikata M, Maeda S, et al. Host-pathogen relationship in retreated tuberculosis with major rifampicin resistance-conferring mutations. Front Microbiol. 2023 Jul 4;14:1187390. | Pubmed abstract
Hellberg Å, Arsenovic MG, Sørvoll IH, et al. A novel nonsense variant in RHAG underlies a Nordic Rh_null phenotype. Vox Sang. 2023 Aug;118(8):690-94. Epub 2023 Jun 2. | Pubmed abstract
Hinton R, Haji R, Kaczmarski R, et al. Hyperhaemolysis caused by anti-HI antibodies in a patient with myelodysplastic syndrome following a first ever red cell transfusion. Transfus Med. 2023 Aug;33(4):349-51. Epub 2023 Apr 25.
Hoad VC, Seed CR, Kiely P, et al. Removal of UK-donor deferral for variant Creutzfeldt-Jakob disease: A large donation gain in Australia. Vox Sang. 2023 Aug 11. Epub ahead of print. | Pubmed abstract
Hu J, Safir F, Chang K, et al. Rapid genetic screening with high quality factor metasurfaces. Nat Commun. 2023 Jul 26;14(1):4486. | Pubmed abstract
Hwang JH, Tung JP, Harkin DG, et al. Investigation of the effect of pre-analytical factors on particle concentration and size in cryoprecipitate using nanoparticle tracking analysis. Transfus Med. 2023 Jul 22. Epub ahead of print. | Pubmed abstract
Jackson CL, Keeton JZ, Eason SJ, et al. Identifying familial hypercholesterolemia using a blood donor screening program with more than 1 million volunteer donors. JAMA Cardiol. 2019 Jul 1;4(7):685-89. | Pubmed abstract
* Jacobs JW, Shih AW, Lombard FW, et al. A multidisciplinary comparison of transfusion and perioperative support for high-risk cardiac surgery at three large academic centres in North America. Transfus Med. 2023 Aug;33(4):337-48. Epub 2023 May 12.
Kampitsi CE, Nordgren A, Mogensen H, et al. Neurocutaneous syndromes, perinatal factors, and the risk of childhood cancer in Sweden. JAMA Netw Open. 2023 Jul 3;6(7):e2325482 | Pubmed abstract
Kenmegne GR, Zou C, Lin Y, et al. A prophylactic TXA administration effectively reduces the risk of intraoperative bleeding during open management of pelvic and acetabular fractures. Sci Rep. 2023 Aug 2;13(1):12570. | Pubmed abstract
Kenney MO, Wilson S, Shah N, et al. Biopsychosocial factors associated with pain and pain-related outcomes in adults and children with Sickle Cell Disease: A Multivariable Analysis of the GRNDaD Multi-Center Registry. J Pain. 2023 Aug 4:S1526-5900(23)00494-7. Epub ahead of print. | Pubmed abstract
Kohn R, Harhay MO, Weissman GE, et al. A data-driven analysis of ward capacity strain metrics that predict clinical outcomes among survivors of acute respiratory failure. J Med Syst. 2023 Aug 5;47(1):83.
Kumari N, Gomber S, Dewan P, et al. COVID-19 antibody response in patients with thalassemia. Cureus. 2023 Jun 17;15(6):e40567. | Pubmed abstract
Laurén E, Sankkila L, Pettilä V, Kerkelä E. Immunomodulatory properties of packed red blood cells during storage. Transfus Med Hemother. 2022 Nov 4;50(3):208-17. | Pubmed abstract
* Latour C, Gaussen A, Beaudoin J, et al. Incidence of acute haemolytic transfusion reaction among ABO-incompatible recipients transfused with A₃ blood: A case series. Vox Sang. 2023 Aug 17. Epub ahead of print.
LeBlanc MR, LeBlanc TW, Yang Q, et al. A mobile app to support self-management in patients with multiple myeloma or chronic lymphocytic leukemia: Pilot randomized controlled trial. JMIR Cancer. 2023 Jul 6;9:e44533. | Pubmed abstract
Lee SB, Kim JH, Kwon YW. The first room-temperature ambient-pressure superconductor Nat Rev Phys. 22 July 2023.
Lee JJ, Tsang VWY, Chan MMK, et al. Virtual reality simulation-enhanced blood transfusion education for undergraduate nursing students: A randomised controlled trial. Nurse Educ Today. 2023 Jul 13;129:105903. Epub ahead of print.
Lei H, Zhang H, Guo L, et al. Identification of a novel variant c.761C>T on ABO*B.01 gene in ABO glycosyltransferases associated with B_weak phenotype. Vox Sang. 2023 Aug 11. Epub ahead of print.
* Leung AKC, Lam J, Wong AHC, et al. Iron deficiency anemia: An updated review. Curr Pediatr Rev. 2023 Jul 27. Epub ahead of print.
Li S, Ren Q, et al. Integrating multi-omics features for blood-based multi-cancer early detection. ASCO Breakthrough 2023. August 3-5, 2023. Abstract 156.
Li L, Wang Z, Wang K, et al. Paintable bioactive extracellular vesicle ink for wound healing. ACS Appl Mater Interfaces. 2023 May 31;15(21):25427-36. Epub 2023 May 19.
Limothai U, Tachaboon S, Dinhuzen J, et al. Seroprevalence of leptospirosis among blood donors in an endemic area. Sci Rep. 2023 Jul 31;13(1):12336. | Pubmed abstract
Lorusso A, Croxon H, Faherty-O'Donnell S, et al. The impact of donor biological variation on the quality and function of cold-stored platelets. Vox Sang. 2023 Jul 13. Epub ahead of print. | Pubmed abstract
MacAdam AJ, Marcelo Munoz M, El Hage J, et al. Low energy blue pulsed light-activated injectable materials for restoring thinning corneas Adv Funct Mater Epub 2023 19 July
* McLaren PJ, Porreca I, Iaconis G, et al. Africa-specific human genetic variation near CHD1L associates with HIV-1 load. Nature. 2023 Aug 2. Epub ahead of print. | Pubmed abstract
McQuilten ZK, Thao LTP, Pasricha SR, et al. Effect of low-dose aspirin versus placebo on incidence of anemia in the elderly : A secondary analysis of the aspirin in reducing events in the elderly trial. Ann Intern Med. 2023 Jul;176(7):913-21. Epub 2023 Jun 20. Erratum in: Ann Intern Med. 2023 Jul 25;:
Mihalca D, Ahmad A, Mehta D, et al. Emergency red cell exchange for the management of acute complications in sickle cell disease: Automated versus manual. Transfus Med. 2023 Aug;33(4):287-9. Epub 2023 Mar 8.
Mina MJ, Kula T, Leng Y, et al. Measles virus infection diminishes preexisting antibodies that offer protection from other pathogens. Science. 2019 Nov 1;366(6465):599-606. | Pubmed abstract
Mirlashari MR, Vetlesen A, Nissen-Meyer LSH, Hetland G. Effects of storage on quality and function of acid-treated platelets with reduced HLA Class I surface expression. Transfus Med. 2023 Aug;33(4):329-36. Epub 2023 Jun 25. | Pubmed abstract
Mitra B, Bernard S, Gantner D, et al.; PATCH-Trauma study investigators; PATCH-Trauma Study investigators. Protocol for a multicentre prehospital randomised controlled trial investigating tranexamic acid in severe trauma: the PATCH-Trauma trial. BMJ Open. 2021 Mar 15;11(3):e046522. | Pubmed abstract
Mortensen SJ, Gjerding LAM, Exsteen MB, et al. Reduced susceptibility to COVID-19 associated with ABO blood group and pre-existing anti-A and anti-B antibodies. Immunobiology. 2023 Jul;228(4):152399. Epub 2023 May 30. | Pubmed abstract
Munawar Ali R, Abid M, Zafar S, et al. Management of severe hemophilia A: Low-dose prophylaxis vs. on-demand treatment. Cureus. 2023 Jul 5;15(7):e41410. | Pubmed abstract
Ng SC, Chu AWH, Chan WM, et al. Re-examine the transfusion transmitted risk of SARS-CoV-2 virus during a major COVID-19 outbreak in 2022. Transfus Med. 2023 Aug;33(4):315-19. Epub 2023 Jun 7.
Pattiya Arachchillage KGG, Chandra S, Williams A, et al. Electrical detection of RNA cancer biomarkers at the single-molecule level. Sci Rep. 2023 Aug 1;13(1):12428. | Pubmed abstract
Pieters R, de Groot-Kruseman H, Fiocco M, et al. Improved outcome for ALL by prolonging therapy for IKZF1 deletion and decreasing therapy for other risk groups. J Clin Oncol. 2023 Jul 17:JCO2202705. Epub ahead of print. | Pubmed abstract
* Povshedna T, Swann SA, Levy SLA, et al. Global prevalence of chronic pain in women with HIV: A systematic review and meta-analysis. Open Forum Infect Dis. 2023 Jul 15;10(8):ofad350. | Pubmed abstract
Richardson PG, Facon T, Venner CP, et al. Late versus early response and depth of response are associated with improved outcomes in patients with newly diagnosed multiple myeloma enrolled in the TOURMALINE-MM2 trial. eJHaem. Epub 2023 Aug 3
Risso MA, Deffune E, Luzo ÂCM. Using umbilical cord blood as a source of paediatric packed red blood cells: Processing and quality control. Vox Sang. 2023 Aug;118(8):637-46. Epub 2023 Jun 5.
Santos Carreira A, Salas MQ, Remberger M, et al. Interaction between high-dose intravenous busulfan and post-transplantation cyclophosphamide on hemorrhagic cystitis after allogeneic hematopoietic cell transplantation. Transplant Cell Ther. 2023 Jul 10:S2666-6367(23)01390-8. Epub ahead of print.
Sayed SZ, Abd El-Hafez AH, Abu El-Ela MA, et al. OPG/RANK/RANKL axis relation to cardiac iron-overload in children with transfusion-dependent thalassemia. Sci Rep. 2023 Aug 2;13(1):12568. | Pubmed abstract
Schucht JE, Harbrecht BG, Bond LM, et al. Plasma resuscitation improves and restores intestinal microcirculatory physiology following haemorrhagic shock. Vox Sang. 2023 Aug 10. Epub ahead of print. | Pubmed abstract
Semko JH, Longoria J, Porter J, et al. Examining the influence of pain and fatigue on neurocognitive functioning in adolescents and young adults with sickle cell disease. Pediatr Blood Cancer. 2023 Aug 10:e30621. Epub ahead of print.
* Shah R, Petch J, Nelson W, et al. Nailfold capillaroscopy and deep learning in diabetes. J Diabetes. 2023 Feb;15(2):145-51. Epub 2023 Jan 15 | Pubmed abstract
Shahswar R, Beutel G, Gabdoulline R, et al. Fludarabine, cytarabine, and idarubicin with or without venetoclax in patients with relapsed/refractory acute myeloid leukemia. Haematologica. 2023 Jul 20. Epub ahead of print.
Shimony S, Flamand Y, Valtis YK, et al. Effect of BMI on toxicities and survival among adolescents and young adults treated on DFCI Consortium ALL Trials. Blood Adv. 2023 Jul 11:bloodadvances.2023009976. Epub ahead of print.
Soto-Mora JA, Gómez-Espitia LM, Lasalvia P, et al. Effectiveness and safety of caplacizumab in acquired thrombotic thrombocytopenic purpura: health technology assessment and classification according to the methodology established in Colombia. Int J Technol Assess Health Care. 2023 Jul 21;39(1):e48. | Pubmed abstract
* Stamatakis E, Ahmadi MN, Friedenreich CM, et al. Vigorous intermittent lifestyle physical activity and cancer incidence among nonexercising adults: The UK Biobank Accelerometry Study. JAMA Oncol. 2023 Jul 27. Epub ahead of print. | Pubmed abstract
* Stoklosa K, Elfaki LA, Ding C, et al. Vaccine-incentivized blood donation: A survey of public perceptions in Canada. Vox Sang. 2023 Aug;118(8):624-36. Epub 2023 Jun 29. | Pubmed abstract
Sung H, Nisotel L, Sedeta E, et al. Racial and ethnic disparities in survival among people with second primary cancer in the US. JAMA Netw Open. 2023 Aug 1;6(8):e2327429. | Pubmed abstract
Szijj PA, Gray MA, Ribi MK, et al. Chemical generation of checkpoint inhibitory T cell engagers for the treatment of cancer. Nat Chem. 2023 Jul 24. Epub ahead of print. | Pubmed abstract
Tada A, Takeuchi N, Shoji K, Kawano R. Nanopore filter: A method for counting and extracting single DNA molecules using a biological nanopore. Anal Chem. 2023 Jul 4;95(26):9805-12. Epub 2023 Jun 6.
Takamatsu H, Matsuda T, Mizuno S, et al.; Multiple Myeloma Working Group in the Japanese Society for Transplantation and Cellular Therapy. Changing trends in the risk factors for second primary malignancies after autologous stem cell transplantation for multiple myeloma before and after the introduction of proteasome inhibitors and immunomodulatory drugs. Haematologica. 2023 Jul 20. Epub ahead of print.
Tandon A, Roder-DeWan S, Chopra M, et al. Adverse birth outcomes among women with 'low-risk' pregnancies in India: findings from the Fifth National Family Health Survey, 2019-21. Lancet Reg Health Southeast Asia. 2023 Jul 23;15:100253. | Pubmed abstract
Treml A, Joshi SA, Stephens LD, et al. Apheresis medicine education during the early phase of the COVID-19 pandemic. Transfusion. 2023 Aug;63(8):1580-9.
van den Berg K, Murphy EL, Louw VJ, et al. Motivations for blood donation by HIV-positive individuals on antiretrovirals in South Africa: A qualitative study. Transfus Med. 2023 Aug;33(4):277-86. Epub 2023 Feb 17. | Pubmed abstract
Wang B, Wen X, Zhang R, et al. Homoharringtonine-based induction therapy reduces the recurrence rate of pediatric acute myeloid leukemia after allogeneic hematopoietic stem cell transplantation. Cell Transplant. 2023 Jan-Dec;32:9636897231183559. | Pubmed abstract
Westin JR, Oluwole OO, Kersten MJ, etal.; ZUMA-7 Investigators; Kite Members. Survival with axicabtagene ciloleucel in large B-cell lymphoma. N Engl J Med. 2023 Jul 13;389(2):148-57. Epub 2023 Jun 5
Wu D, Hanison J. Critical care length of stay and support requirements for patients postpancreas transplant. Prog Transplant. 2023 Jul 30:15269248231189875. Epub ahead of print.
Yuen MF, Asselah T, Jacobson IM, et al.; REEF-1 Study Group. Efficacy and safety of the siRNA JNJ-73763989 and the capsid assembly modulator JNJ-56136379 (bersacapavir) with nucleos(t)ide analogues for the treatment of chronic hepatitis B virus infection (REEF-1): a multicentre, double-blind, active-controlled, randomised, phase 2b trial. Lancet Gastroenterol Hepatol. 2023 Jul 10:S2468-1253(23)00148-6. Epub ahead of print.
Zhao Q, Liu G, Liu F, et al. An enzyme-based system for extraction of small extracellular vesicles from plants. Sci Rep. 2023 Aug 25;13(1):13931 | Pubmed abstract
Zhu CT, Yin JY, Chen XH, et al. Appraisal of evidence reliability and applicability of Paxlovid as treatment for SARS-COV-2 infection: A systematic review. Rev Med Virol. 2023 Aug 14:e2476. Epub ahead of print.
Zurko J, Nizamuddin I, Epperla N, et al. Peri-CAR-T practice patterns and survival predictors for all CAR-T patients and post-CAR-T failure in aggressive B-NHL. Blood Adv. 2023 Jun 27;7(12):2657-69. | Pubmed abstract

Monthly newsletter - August 2023

General

Canada

ORBCoN resources:

Australia

Djibouti

Ghana

Hong Kong

India

Ireland

Kenya

Kuwait

Malta

Namibia